Permanganate in Opium Poisoning
نویسنده
چکیده
Sir,?This treatment has not found by any means strong support, although founded on good chemical reason, i.e., that potassium permanganate decomposes morphia. If is naturally only useful to render harmless the morphia tvhich is in the alimentary canal and so unabsorbed. No one who understands what poisoning is, would expect this drug to be of service when a case is seen late, and a lethal dose has already entered the blood stream. For poisoning is the result of a chemical union of the toxic body with molecules of living protoplasm or of fluids of the body and when this action has taken place, treatment can only combat adverse symptoms, due to upset of function performed by the altered molecules. To expect that such an oxidizing agent as potassium permanganate will be absorbed as such from the alimentary canal or subcutaneous tissue is futile, as it is to hope for it to decompose morphia in the blood stream or kick it out from a chemical union with tissue protoplasm. A recent case, treated with this drug, clearly shows that good will result, provided the patient be seen early and before a lethal dose has been absorbed. Death resulted because such an absorption had already occurred. The following is the analysis result:? (1) The presence of morphia in quantity was detected in the urine, but no meconic acid. (2) The presence of morphia in quantity and a mere trace of meconic acid was detected in a mixture of pieces of liver, spleen and kidney. (3) The presence of meconic acid in quantity, but no morphia was detected in the stomach washings (washing out was performed at once, when the patient was seen, tirst with warm water, and then with solution of potassium permanganate). (4) Both morphia and meconic acid were detected in the
منابع مشابه
Case of Opium Poisoning
1/ To the Editor of " The Indian Medical Gazette.' Sir-I send you the following notes of a case for publicatl0Kam Slioshi Mandal, Hindu, aged about 18 years, was brought to the Police Case HospitalI Alipore, at 12-30 P.M., 12th September 1901, with the following history He had been in the habit for months past of taking a morning and evening dose of bazaar opium, about ten grains each time, to ...
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